![]() ![]() Formolized suspensions enable detection of flagellar agglutinins, whereas alcohol-extracted organisms, devoid of flagellar antigens permit the detection of somatic agglutinins. The classification of the organism responsible for the particular infection, according to the Kaufmann-White scheme (1), depends in part on the differentiation of these agglutinins by the use of chemically treated bacterial suspensions. Infection with an organism of this group will give rise to the production of flagellar and somatic agglutinins. One such problem and the manner in which it has been partially overcome is exemplified by the classification of organisms in the Salmonella group. The complex antigenic structure of bacteria raises many practical difficulties in the use of intact bacteria as diagnostic serological reagents, since the presence of several reactive antigenic groupings may confuse the significance of positive reactions.
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